021-51111890
购物车（）
sales@molnova.cn
FtsZ inhibitor C109
CAS No. ——
FtsZ inhibitor C109 ( Compound 10126109 )
产品货号. M17105 CAS No. ——
FtsZ抑制剂C109 (Compound 10126109)是一种广谱抗菌化合物，可抑制细胞分裂蛋白FtsZ，抑制FtsZ GTPase活性，IC50为8.2 uM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称FtsZ inhibitor C109
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述FtsZ抑制剂C109 (Compound 10126109)是一种广谱抗菌化合物，可抑制细胞分裂蛋白FtsZ，抑制FtsZ GTPase活性，IC50为8.2 uM。
-
产品描述FtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2 uM; inhibits both the GTPase and polymerization activities of purified B. cenocepacia FtsZ, prevents divisome formation by altering the localization of the essential cell division protein FtsZ; displayes antibacterial activity against Gram-positive and Gram-negative cystic fibrosis pathogens, including Mycobacterium abscessus, C109 effectively cleared B. cenocepacia infection in the Caenorhabditis elegans model and exhibited additive interactions with clinically relevant antibiotics.
-
体外实验——
-
体内实验——
-
同义词Compound 10126109
-
通路GPCR/G Protein
-
靶点Antibacterial
-
受体Antibacterial
-
研究领域——
-
适应症——
化学信息
-
CAS Number——
-
分子量285.292
-
分子式C9H7N3O4S2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称methyl 2-((4-nitrobenzo[c][1,2,5]thiadiazol-5-yl)thio)acetate
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Hogan AM, et al. Antimicrob Agents Chemother. 2018 Oct 8. pii: AAC.01231-18. doi: 10.1128/AAC.01231-18.
2. Scoffone VC, et al. Front Microbiol. 2015 Aug 5;6:815. doi: 10.3389/fmicb.2015.00815.
产品手册
关联产品
-
Peimisine
哌咪辛能影响M-受体，兴奋β-受体，抑制体内钙的释放，促进一氧化氮的释放，从而松弛气管平滑肌，缓解哮喘。
-
Polymyxin B nonapept...
Polymyxin B nonapeptide, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probably by binding to the bacterial lipopolysaccharide (LPS)
-
F7H
F7H 是卷曲蛋白受体 (Frizzled receptor) FZD7 拮抗剂 (IC50: 1.25 μM)。卷曲受体 (FZD) 影响着 Wnt 信号传导，介导胚胎发育和组织稳态。F7H 是 FZD7 跨膜结构域 (TMD) 的有效配体。
